Inception and Significance of Myoblasts
Keywords:
Myofibril, cytokines, skeletal system, Hepatocytes, MyostatinAbstract
Adult mammalian skeletal muscle regeneration involves many proteins and signalling networks. Cytokines influence skeletal muscle development. Myofibrillar repair and regeneration depend on cytokines generated by cells of immune system, at injury site of muscle. Skeletal muscle is a key generator of cytokines. Muscle-released cytokines (myokines) may have endocrine effects on regulation of metabolism. Available reports suggest that myogenic differentiation and regeneration are governed by autocrine cytokines released by muscles. Present review focus on cytokines that (a) expression of muscle cells and (b) have a myogenic role. This group of cytokines controls the entire myogenic process. How cytokines create a regulatory network is an intriguing and crucial topic. To fully explore the therapeutic potential of cytokines, functional studies must pinpoint their in vivo source.
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