Design and Development of Biopolymer - Based Molecularly Imprinted Polymer Nanoparticles for Analytical Sensing Applications
Keywords:
Nanoparticles, Biopolymers, Fabrication Methods, Characterization Parameters, Medicine and Biotechnology, Biocompatible Materials, Drug Delivery, Future ApplicationsAbstract
This research on nanoparticles highlights the recent advancements in utilizing biopolymers, including proteins and polysaccharides, to revolutionize the development of biocompatible and environmentally degradable natural biological materials. The article provides insights into various fabrication methods, such as emulsification, desolvation, coacervation, and electrospray drying. Furthermore, it delves into the comprehensive characterization of nanoparticles, covering parameters like particle size, surface charge, morphology, stability, structure, cellular uptake, cytotoxicity, drug loading, and drug release, while also discussing the relevant measurement techniques. The review explores applications of these biopolymer-based nanoparticles in the fields of medicine and biotechnology and looks ahead to a promising future scope in this area.
Downloads
References
• Ghaani, M., Büyüktaş, D., Carullo, D., & Farris, S. (2022). Development of a New Electrochemical Sensor Based on Molecularly Imprinted Biopolymer for Determination of 4, 4′-Methylene Diphenyl Diamine. Sensors, 23(1), 46.
• Kamyab, H., Chelliapan, S., Tavakkoli, O., Mesbah, M., Bhutto, J. K., Khademi, T., ... & ALJohani, A. A. (2022). A review on carbon-based molecularly-imprinted polymers (CBMIP) for detection of hazardous pollutants in aqueous solutions. Chemosphere, 308, 136471.
• Kutner, W., & Sharma, P. S. (Eds.). (2018). Molecularly imprinted polymers for analytical chemistry applications (Vol. 28). Royal Society of Chemistry.
• Mahmoudpour, M., Torbati, M., Mousavi, M. M., de la Guardia, M., & Dolatabadi, J. E. N. (2020). Nanomaterial-based molecularly imprinted polymers for pesticides detection: Recent trends and future prospects. TrAC Trends in Analytical Chemistry, 129, 115943.
• Ramanavicius, S., & Ramanavicius, A. (2022). Development of molecularly imprinted polymer based phase boundaries for sensors design. Advances in Colloid and Interface Science, 305, 102693.
• Ramanavicius, S., Jagminas, A., & Ramanavicius, A. (2021). Advances in molecularly imprinted polymers-based affinity sensors. Polymers, 13(6), 974.
• Santos, A. C. F., de Araújo, O. R., Moura, F. A., Khan, S., Tanaka, A. A., Santana, A. E. G., ... & Goulart, M. O. (2021). Development of magnetic nanoparticles modified with new molecularly imprinted polymer (MIPs) for selective analysis of glutathione. Sensors and Actuators B: Chemical, 344, 130171.
• Sellergren, B. (Ed.). (2000). Molecularly imprinted polymers: man-made mimics of antibodies and their application in analytical chemistry. Elsevier.
